By Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas
Probiotic bacteria play important roles in the regulation of human health but until recently, the mechanisms that explain how probiotic bacteria regulate so many aspects of human health have remained elusive. This puzzle is starting to be solved.
When bacteria ferment dietary fibers in the colon, they create compounds referred to as postbiotic metabolites. During the past two decades, scientific studies have been explaining how various classes of postbiotic metabolites regulate many aspects of human health, especially the immune system. Postbiotic metabolites are now recognized as critically important health-regulating compounds for the whole body.
Dr. Ohhira’s probiotics are produced in a multi-year fermentation process. Independent studies report that Dr. Ohhira’s Probiotics contain over 500 postbiotic metabolites.
The GUT Immune System:
- A large percentage of the body’s immune system are located in the intestinal tract. Some estimates suggesting that over 70% of the body’s immune cells are located in the gastrointestinal tract.1
- Dysbiosis is associated with many intestinal & extra-intestinal disorders.2
- 28 studies have been published, which report that probiotics exert antiviral effects by direct inactivation of viruses or by stimulating the immune system response to viral infections.3
Thus, maintaining a healthy gut microbiome and a healthy well-functioning gastrointestinal tract are critical for the maintenance of a healthy immune system.
Dr. Ohhira’s Probiotics is the world-leader in directly delivering postbiotic metabolites. This rapidly helps resolve dysbiosis-related GI problems, which in turn, helps people maintain a healthy microbiome and a healthy immune system.
Postbiotic metabolites in Dr. Ohhira’s Probiotics help in the following ways:
- Short-chain fatty acids (SCFAs) promote the growth of probiotic bacteria
- SCFA butyrate provides the energy for growth of healthy new intestinal cells
- Various SCFAs have direct anti-inflammatory activity
- Postbiotic metabolites knows as antimicrobial peptides directly kill pathogens
- Some postbiotic metabolites regulate, stimulate and/or modulate immune responses
- Production of nutritional postbiotic metabolites; B-vitamins, vitamin K & amino acids
- Some postbiotic metabolites have antioxidant activity
- Postbiotic metabolites named fulvic acids promote nutrient absorption & detoxification
Take Dr. Ohhira’s Probiotics, a fermented food probiotic that contains probiotics, prebiotics and over 500 postbiotic metabolites to support your health and your immune system.
Furness JB, et al. Nutrient Tasting and Signaling Mechanisms in the Gut. II. The Intestine as a Sensory Organ: Neural, Endocrine, and Immune Responses. Am J Physiol. 1999 Nov;277(5):G922-8.
2 Carding S, et al. Dysbiosis of the gut microbiota in disease. Microbial Ecology in Health and Disease. 2015;26(s2).
3 Lehtoranta L, et al. Probiotics in Respiratory Virus Infections. Eur J Clin Microbiol Infect Dis. Aug 2014;33*8):1289-1302.