By Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas
The Silent Threat of Mold and Mycotoxins
Mold and its toxins, mycotoxins, are a growing public health concern. Dr. Ritchie Shoemaker aptly describes illnesses related to mold exposure as a “silent epidemic.”i
Pediatrician Dr. Scott McMahon echoes this concern, highlighting the prevalence of undiagnosed mold-related illnesses.ii
The Rise of Mold-Related Illnesses
Mold growth occurs naturally, but its impact on human health has increased significantly in recent decades. This can be attributed to two primary factors:
- Mold-contaminated food: Improper handling and storage methods lead to mycotoxin contamination in grains, nuts, spices, and other food items. It’s estimated that a quarter of the world’s food crops are affected by mold.iii
- Water-damaged buildings: Leaks, damp areas, and flooding create ideal environments for mold growth. Additionally, mold thrives in ventilation systems, exposing occupants to spores and mycotoxins. Superstorms like Katrina and recent hurricanes further exacerbate this issue.iv
Schools and Children at Risk
Studies reveal a disturbing trend of mold found in schools, potentially affecting millions of children and educators. This exposure can have a significant impact on health and learning.v, vi
Invisible Enemy: Mold Spores and Their Impact
Microscopic mold spores are easily inhaled, causing various health problems. Even small amounts of mold can release millions of spores, leading to a range of illnesses.
Mycotoxins and Their Devastating Effects
Mycotoxins are highly toxic, causing a wide range of health issues at incredibly low exposure levels. They damage the body through oxidative stress and free radical production, harming DNA, the immune and nervous systems, and vital organs like the liver and kidneys.vii
The Crucial Role of Glutathione
Glutathione, the body’s most abundant antioxidant, plays a critical role in mitigating the harmful effects of mold and mycotoxins. Exposure to these toxins depletes glutathione levels and hinders the body’s ability to produce more. This weakens the body’s defenses, accelerating damage to tissues and organs.
Glutathione and Detoxification
Glutathione also plays a vital role in detoxifying mycotoxins. Glutathione S-transferases, a group of enzymes dependent on glutathione, help metabolize, detoxify, and eliminate mycotoxins. Sufficient levels of reduced (active) glutathione and these enzymes are crucial for preventing and treating mycotoxin-related illnesses.viii,ix,x
Glutathione Deficiency and Treatment
Boosting glutathione levels can be challenging due to various factors. Dietary deficiencies in essential amino acids like cysteine, glycine, and glutamate, which are the building blocks of glutathione, can hinder its production. Liver dysfunction, caused by factors such as alcohol abuse, toxins, or diseases, can significantly impair glutathione synthesis. Oxidative stress, resulting from an excess of harmful free radicals, can rapidly deplete glutathione as it acts as an antioxidant. Aging naturally leads to a decline in glutathione production, making it harder to maintain optimal levels. Chronic stress can also deplete glutathione stores. Certain medications, including acetaminophen and chemotherapy drugs, can further reduce glutathione levels. Additionally, genetic factors, such as enzyme deficiencies involved in glutathione synthesis, can contribute to reduced production.
Clinicians often find glutathione deficiency in patients exposed to water-damaged buildings. Therefore, glutathione and its precursors become essential components of treatment protocols for mold-related illnesses.
Boosting Glutathione Levels with Probiotics
A promising approach involves a specific probiotic strain: Lactobacillus fermentum ME-3. This probiotic actively synthesizes glutathione. Studies show that daily supplementation with ME-3 for three weeks significantly increased the ratio of reduced to oxidized glutathione in individuals.xi
Essential Formulas® and Lactobacillus fermentum ME-3
Essential Formulas® offers Reg’Activ® products containing ME-3 alongside supplements supporting specific needs like immune function, heart health, or liver health. They also provide Essential ME-3®, containing only ME-3, easily added to any healthcare regime.
Further Resources
- Dr. Ross Pelton’s article on ME-3: https://naturalpharmacist.net/blog/?category=Lactobacillus%20fermentum%20ME-3
- Information on Reg’Activ® products: https://essentialformulas.com/products/reg-activ/
In conclusion, mold and mycotoxins pose a significant health threat. By raising awareness and understanding the importance of glutathione, we can empower individuals to protect themselves and explore potential treatment options.
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