Postbiotic Metabolites are the next frontier of microbiome science
By Ross Pelton, RPh, PhD, CCN
The term microbiome refers to the bacteria that reside in the gastrointestinal tract. Scientists realize that the microbiome is more than just microbes. The microbiome is the entire gastrointestinal ecosystem, which consists of bacteria and the multitude of compounds the bacteria produce, which are referred to as postbiotic metabolites.
Studies now reveal that postbiotic metabolites are vast master command center that is involved, either directly or indirectly, in regulating and controlling virtually everything that happens in our bodies. This is why it is so critical for people to learn how to create and maintain a healthy microbiome.
Postbiotic Metabolites: The New Microbiome Frontier
To date, around 500 postbiotic metabolites have been identified. Categories of postbiotic metabolites that have been discovered to date include vitamins, amino acids, nucleic acids, organic acids, lipids, steroids, saccharides, polyphenols, enzymes, antioxidants, terpenes, antimicrobial peptides, which function as natural antibiotics, and anti-inflammatory compounds.
It is becoming more and more apparent that just considering bacteria when discussing the microbiome is an incomplete viewpoint. It might be helpful to make a comparison between the microbiome and NASA’s Mission Control Center.
At NASA, the Mission Control Center with its hundreds of computers is the master control center for the whole NASA space program. Similarly, human microbiome with its multitude of postbiotic metabolites is now recognized as the master control center for humans.
Although scientists program the computers, it is the computers, with all their “brain power” that regulate and control the spaceship launches. Similarly, in the microbiome, your probiotic bacteria produce a multitude of postbiotic metabolites, and these are the compounds that play critical roles in regulating and controlling virtually everything that happens in your body. This is why it is so important for people to learn how to create and maintain a healthy microbiome.
Dr. Ohhira’s Probiotics® are not primarily a probiotic product; they are a fermented food product. Like all fermented foods, Dr. Ohhira’s Probiotics do contain probiotic bacteria. However, the power and success of Dr. Ohhira’s Probiotics are predominantly due to the postbiotic metabolites. These are the compounds that have antioxidant and inflammatory activity, rebalance the acid/base level, fight pathogens, support functioning of the immune system, neutralize toxins, synthesize nutrients, help to heal intestinal permeability and communicate with the brain.
Most probiotics just contain probiotic bacteria in a capsule. Those bacteria haven’t done any work yet. They are like a starter culture. Dr. Ohhira’s probiotic bacteria have been working for three years in Dr. Ohhira’s fermentation production process to produce a multitude of postbiotic metabolites.
Each dose of Dr. Ohhira’s Probiotics contains probiotic bacteria, prebiotics foods and most importantly, a multitude of postbiotic metabolites; this is The Dr. Ohhira’s Difference™. At Essential Formulas, we say that Dr. Ohhira’s Probiotics accomplish ‘Rapid Microbiome Restoration’ or ‘Rapid Microbiome Repair’ and why individuals with dysbiosis get fast results with Dr. Ohhira’s Probiotics. Each dose of Dr. Ohhira’s Probiotics delivers a wide range of postbiotic metabolites that accelerate healing in the microbiome ecosystem.
Metabolomics is the branch of science that identifies and measures small molecular compounds that are produced in biological systems like the human GI tract. This branch of science has been rapidly developing because scientists have become increasingly aware that small-molecule metabolites, or what we refer to as postbiotic metabolites, have critical regulatory roles in biological systems.
Recently, an Independent laboratory analyzed Dr. Ohhira’s Probiotics using newly developed scientific technologies. These technologies are capable of identifying the small molecular compounds produced in biological systems. Now scientists can locate these master control compounds called postbiotic metabolites. Postbiotic metabolites are the next frontier in microbiome science.
The recent data analysis revealed that Dr. Ohhira’s Probiotics contain the following postbiotic metabolites:
- 36 Amino Acids
- 215 Peptides
- 10 Nucleic Acids
- 59 Organic Acids
- 43 Lipids
- 14 Steroids
- 19 Saccharides
- 9 Polyphenols
- 3 Terpenes
At Essential Formulas, we are excited to announce this recent analysis and documentation of over 400 postbiotic metabolites in Dr. Ohhira’s Probiotics.
These postbiotic metabolites differentiate Dr. Ohhira’s Probiotics from all the other probiotic products on the market. And, in fact, we re-emphasize that Dr. Ohhira’s Probiotics are not primarily a probiotic. Instead, Dr. Ohhira’s Probiotics are a fermented food product. Each dose of Dr. Ohhira’s Probiotics delivers probiotic bacteria, prebiotic foods and a multitude of postbiotic metabolites.
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