Gut Health and Mood: Exploring the Gut-Brain Connection

By Ross Pelton

RPh, PhD, CCN
Scientific Director, Essential Formulas

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

Original Post Date: December 1, 2021

Ever felt butterflies in your stomach before a big moment? Or noticed how stress can throw off your digestion? That’s no coincidence—your gut and brain are in constant communication. This powerful connection, known as the gut-brain axis, plays a key role in how we feel, think, and function.

Your “Second Brain”: The Gut-Brain Axis

The gut is home to a vast network of neurons—over 100 million—and is linked to the brain via the vagus nerve. This two-way communication system helps regulate mood, digestion, and overall well-being. Researchers continue to explore how this connection influences emotional balance and cognitive function.

Microbiome Matters: Gut Bacteria and Mental Wellness

Your digestive system hosts trillions of microorganisms, including bacteria that help break down food and produce beneficial compounds. Some of these compounds—called postbiotics—include enzymes, vitamins, and neurotransmitters like serotonin and dopamine, which support mood and emotional stability.

A balanced gut microbiome is essential for optimal function. Factors like poor diet, stress, lack of sleep, and certain medications can disrupt this balance. Supporting a diverse population of beneficial bacteria may help maintain digestive comfort and contribute to overall wellness.

Gut Health and Everyday Happiness

Did you know that a large portion of the body’s serotonin is produced in the gut? Serotonin is a key neurotransmitter involved in mood, emotional regulation, and digestive function. While serotonin levels are influenced by many factors, maintaining a healthy gut environment may support its natural production.

Simple lifestyle choices—like eating fiber-rich foods, staying hydrated, getting enough sleep, and managing stress—can help promote a thriving gut ecosystem. Fermented foods and probiotic supplements may also support microbial diversity and digestive health.

Supporting Your Gut Naturally

If you’re looking to support your gut microbiome, consider adding a high-quality probiotic to your daily routine. Dr. Ohhira’s Probiotics® are fermented for three years using a blend of natural ingredients like fruits, vegetables, mushrooms, and seaweeds. They’re non-GMO, 100% vegetarian, and crafted to deliver a broad spectrum of 500 different postbiotic metabolites naturally created by the probiotic bacteria during the multi-year fermentation.

Note: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Dr. Ohhira’s RESET Experience

Curious about how probiotics might fit into your lifestyle? The Dr. Ohhira’s RESET Experience invites you to try a 7-day routine: take 2 capsules twice daily for one week (standard usage is 2 capsules once daily). Many users report feeling more balanced, energized, and comfortable during this experience.

Results may vary. Always consult your healthcare provider before starting any new supplement regimen.

Gut Health FAQs

Can gut health influence how I feel?

Emerging research suggests that the gut microbiome plays a role in producing neurotransmitters that support emotional balance. A diverse and healthy gut environment may contribute to overall well-being.

How can I support the gut-brain connection?

Focus on whole foods, fiber, hydration, sleep, and stress management. Fermented foods and probiotic supplements, like Dr. Ohhira’s Probiotics, may help maintain microbial diversity.

What makes Dr. Ohhira’s Probiotics unique?

Dr. Ohhira’s Probiotics are fermented for three years and contain a wide range of postbiotic compounds. They’re crafted with natural ingredients and designed to support digestive and microbial balance.

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By Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

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