Lactobacillus casei TO-A

Lactobacillus casei is one of the most studied species of probiotic bacteria. In addition to commonly being used in probiotic formulas, it is also frequently used in fermented milk products.

Extensive research in animals and humans has demonstrated the diverse health benefits of L. casei, spanning from digestive health to immune system support, weight management, and even mental health support, highlighting its potential in a wide range of health conditions.i

According to the WHO, diarrhea is the second leading cause of death in children under five and is a significant problem associated with antibiotic therapies. L. casei has been specifically studied since it has such a positive effect on maintaining normal bowel functioning.ii Numerous studies have reported that strains of L. casei help promote overall intestinal tone and health, especially during challenging conditions.iii

L. casei also has a positive effect on the stomach by helping to control the growth of more harmful strains of bacteria. By helping to maintain a more positive microbiome in the gut, L. casei helps improve overall digestion from the stomach through the intestinal tract.iv, v

Since L. casei promotes a positive balance in the microbiomevi, vii, it also helps nurture the tone and health of the intestinal tract tissues. This dual action can help protect the GI tract’s lining, providing a reassuring potential for digestive health.

Lactobacillus casei has recently been reclassified as Lacticaseibacillus casei. However, searching for L. casei will access studies published under the old and new nomenclature.

 
i Jones RM. Chapter 9 – The se of Lactobacillus casei and Lactobacillus paracasei in Clinical Trials for the Improvement of Human Health. The Mircobiota in Gastrointestinal Pathophysiology. 2017:99-180.
ii Isolauri E, et al.
iii Dietrich CG, et al. Commercially available probiotic drinks containing Lactobacillus casei DN-114001 reduce antibiotic-associated diarrhea. World J Gastroenterol. 2014 Nov 14;20(42):15837-15844.
iv Cats A., et al., Effect of frequent consumption of a Lactobacillus casei-containing milk drink in Helicobacter pylori-colonized subjects. Alliment Pharmacol Ther. 2003 Feb;17(3):429-35.
v Sykora J, et al., Effects of a specially designed fermented milk product containing probiotic Lactobacillus casei DN-114 001 and the eradication of H. pylori in children: a prospective randomized double-blind study. J Clin Gastroenterol. 2005 Sep;39(8):692-8.
vi Archambaud C, et al., Impact of lactobacilli on orally acquired listeriosis. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16684-9.
vii Amdekar S, et al., Antiinflammatory, antimicrobial and immunomodulatory properties of Lactobacillus casei against Enteropathogenic Escherichia coli. From http://www.webmedcentral.com on 02-Oct-2010.