Essential Formulas’ Director Published Paper in Respected Journal

Dallas, TX- February 14, 2023 — Ross Pelton, RPh, PhD, CCN and Essential Formulas Director of Science, had his pioneering scientific article, The Microbiome Theory of Aging (MTA), published in the January 2023 edition of “Integrative Medicine: A Clinician’s Journal (IMJC).

“The Microbiome Theory of Aging explains how a microbial imbalance in the intestinal tract, also called dysbiosis, causes health problems that accelerate biological aging,” said Pelton. “The article highlights Postbiotic Metabolites, the compounds that are created by probiotic bacteria in the colon and play a key role in regulating the structure and function of the gut microbiome and human health.”

Postbiotic Metabolites: The New Frontier in Microbiome Science

A pronounced shift is taking place in microbiome science. Until recently, a large portion of scientific research was devoted to isolating, identifying, and naming different species of bacteria. In the new frontier of microbiome science, much more emphasis is being focused on identifying the compounds that various strains of bacteria produce, learning to understand the health-regulating effects of these compounds, and discovering which strains of bacteria are more efficient at producing these health-regulating compounds and affect many aspects of health and aging.

“This groundbreaking article integrates diet, dysbiosis, gut inflammation, intestinal permeability, and lipopolysaccharides (LPS), bacterial toxins that can cause inflammation and if they reach the bloodstream, into a comprehensible theory of aging,” said Pelton.

To read the scientific paper in its entirety, visit:

To download a pdf click here: The Microbiome Theory of Aging


In 2020 Essential Formulas commemorated its 20th Anniversary of offering scientifically proven probiotic products that empower people to lead healthier lives. EFI was established as the sole U.S. distributor of world-renowned microbiologist Dr. Iichiroh Ohhira’s award-winning probiotic products, Dr. Ohhira’s Probiotics and, in 2015, added the pioneering Reg’Activ® Formulas with probiotic ME-3. For over two decades, EFI has helped drive the evolution of a burgeoning probiotic health industry by providing probiotic supplements widely recognized for replenishing and bestowing excellent transformative health.