Lactobacillus fermentum

By Ross Pelton

RPh, PhD, CCN
Scientific Director, Essential Formulas

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

Oct 12, 2016


Ross Pelton

Dallas, Texas (October 20, 2016) – Essential Formulas Director of Science and Research, Ross Pelton, R.Ph., Ph.D., CCN, was recently chosen to present his poster abstract, “A Glutathione Producing Strain of Probiotic Bacteria–Lactobacillus fermentum ME-3” at the Probiotic Congress: USA held in San Diego, California, October 3-4.

Thirty-six posters were chosen for presentation from over 90 entries. The 2-day Congress explored the development of the next generation of probiotics, prebiotics and functional foods and their impact on human health. The Congress also showcased a series of interactive presentations with leading academic and industry experts, panel discussions and an exhibition area allowing solution providers to highlight their products and services.

“I was honored to be selected to summarize the benefits of the glutathione-producing probiotic strain Lactobacillus fermentum ME-3 to scientists from around the world,” said Dr. Pelton. “Attendees were excited to learn of the discovery of a probiotic strain that can effectively boost glutathione levels in humans, as it has been proven to be one of the most effective proactive actions people can take to strengthen their immune system, prevent illness and promote good health.”

Dr. Pelton’s poster was also chosen for presentation and competition at The American College of Nutrition’s 57th Annual Conference, Translational Nutrition: The Science of Personalized Nutrition, to be held November 9-11 in San Diego, California. Presenters will provide a five-minute overview of their work and answer any questions from the judges. Posters will be judged on criteria including relevance, originality, visual composition as well as scientific methodology and rigor. The winners will be announced at the end of the conference.

Sold under the brand name, Reg´Activ®, ME-3, was discovered in 1995 by award-winning microbiologist Marika Mikelsaar, MD, Ph.D. and her team of research scientists at the University of Tartu, Estonia. ME-3 is being heralded as a breakthrough in health and medicine due to its ability to synthesize glutathione in humans. Glutathione is considered the ‘Master Antioxidant and Detox’ agent, and is now being recognized as a key ‘Biomarker of Aging’.

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Essential Formulas Incorporated (EFI) was established in 2000 as the sole U.S. distributor of world-renowned microbiologist Dr. Iichiroh Ohhira’s award-winning probiotic dietary supplements and skin care products. Always an innovator EFI introduced REG’ACTIV in 2015. As a result of producing glutathione, ME-3 improves antioxidant support and enhances detoxification throughout the body. A family-owned and operated business, EFI was founded on the philosophy of providing high-quality preventative, supportive and comprehensive pro-health products for the entire family.

The History & Discovery of Lactobacillus fermentum ME-3

The Glutathione Producing Probiotic

By Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas


Professor Marika Mikelsaar, M.D., Ph.D., a professor emeritus in the department of microbiology at the University of Tartu, is credited with the discovery of Lactobacillus fermentum ME-3.

Professor Mikelsaar and her team of scientists in the Department of Microbiology at the University of Tartu were highly qualified to study the properties of ME-3 due to their years of research on Lactobacillus bacteria and the ecology of the human gastrointestinal tract. In fact, for over 20 years, Professor Mikelsaar and her colleagues worked with the Russian Space Program studying the effects that space flight had on the intestinal bacteria of astronauts.

Lactobacillus fermentum ME-3 was isolated from the intestinal tract of a healthy 1-year old Estonian child on March 2, 1995. At the time, the scientists at Tartu were testing a wide range of Lactobacillus bacteria for antioxidant activity. While most strains failed one strain exhibited extremely high antioxidant properties. That strain was ME-3.

The University of Tartu is located in Estonia, which is a small country of 1.3 million people located in Eastern Europe and borders on Russia. King Gustavus Adolphus of Sweden founded the University of Tartu in 1632, which makes it one of the oldest universities in the world.

The University of Tartu has also rated as one of the top universities in the world academically. In 2016, the University of Tartu was ranked in the top 2% of universities in the world (347th out of over 16,000 universities worldwide), and it is in the top 1% of the world’s most cited universities in 10 scientific areas of research.

Professor Mikelsaar is recognized as one of the world’s leading experts in the fields of medical microbiology, human microbial ecology, and biomedicine. In 2007, Professor Mikelsaar received the European Union (EU) award as “European Union Woman Inventor and Innovator” for the discovery of Lactobacillus fermentum ME-3.

Contact: Kelly Charles
Corporate Communications/Essential Formulas Incorporated
Kelly@kcharlescommunications.com
972.743.0373

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By Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

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