Overview on Microbiome and Mental Health

By Ross Pelton

RPh, PhD, CCN
Scientific Director, Essential Formulas

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

Dec 07, 2016


How the Microbiome May Affect Mental State

I would like to make the following observations based on the above-mentioned study, which I believe is a very important insight into the microbe and mental health.

  • This study shows that chronic stress decreases Microbiome diversity
  • In addition to the stress-induced changes in the Microbiome, the rats also began experiencing loss of pleasure and “despair-like” behavior. 
  • And…. what is really fascinating is that when these microorganisms were transferred from the stressed rats to a new group of animals that had not been stressed, Dr. Emily Jutkiewicz found that these new animals also began to demonstrate these same behavioral changes after 5 days, suggesting a potential causal mechanism. (i.e.…the changes in the Microbiome are causing the behavioral changes)
  • In human studies…similar changes in the Microbiome are found in people with bipolar disorder and major depression…resulting in high anxiety, sleep problems and increased incidence of other general health problems.

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By Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas

Ross Pelton is a pharmacist, nutritionist, author and a health educator who is widely recognized as the world’s leading authority on drug-induced nutrient depletions. He was named one of the top 50 most influential pharmacists in the United States by American Druggist magazine for his work in Natural Medicine.

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